Mechanisms of immune tolerance to allergens in children
نویسندگان
چکیده
منابع مشابه
Mechanisms of immune tolerance to allergens in children
Because the prevalence of allergic diseases has significantly increased in recent years, understanding the causes and mechanisms of these disorders is of high importance, and intense investigations are ongoing. Current knowledge pinpoints immune tolerance mechanisms as indispensable for healthy immune response to allergens in daily life. It is evident that development and maintenance of allerge...
متن کاملMechanisms of allergen-specific immunotherapy and immune tolerance to allergens
Substantial progress in understanding mechanisms of immune regulation in allergy, asthma, autoimmune diseases, tumors, organ transplantation and chronic infections has led to a variety of targeted therapeutic approaches. Allergen-specific immunotherapy (AIT) has been used for 100 years as a desensitizing therapy for allergic diseases and represents the potentially curative and specific way of t...
متن کاملMechanisms of immune-tolerance to allergens on the mucosal surfaces
The immune system is a highly interactive network, which makes it’s decisions on the basis of all body tissues, infections, normal flora bacteria and almost any environmental agents. In recent years, regulatory T cells (TReg) cells have become a prime target for strategies aimed at inducing tolerance to ffod antigens. Immune tolerance in the context of allergy can be defined as persistence of e...
متن کاملMechanisms of immune tolerance to allergens: role of IL-10 and Tregs.
During the past 20 years, major advances have been made in understanding the molecular and cellular mechanisms of allergen tolerance in humans. The demonstration of T cell tolerance, particularly that mediated by the immune-suppressive functions of IL-10, led to a major conceptual change in this area. Currently, the known essential components of allergen tolerance include the induction of aller...
متن کاملHeated Allergens and Induction of Tolerance in Food Allergic Children
Food allergies are one of the first manifestations of allergic disease and have been shown to significantly impact on general health perception, parental emotional distress and family activities. It is estimated that in the Western world, almost one in ten children have an IgE-mediated allergy. Cow's milk and egg allergy are common childhood allergies. Until recently, children with food allergy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Korean Journal of Pediatrics
سال: 2013
ISSN: 1738-1061,2092-7258
DOI: 10.3345/kjp.2013.56.12.505